Pre-Exposure Prophylaxis, or PrEP, is a once-daily medication that greatly lowers at-risk people from getting HIV. If taken as prescribed, PrEP is 99% effective at preventing HIV from sexual encounters and at least 74% effective at preventing HIV from injection drug use. PrEP is only for people that do not already have HIV.

Prevention Assistance Program Interventions (PAPI) is the Ohio Department of Health’s HIV prevention program. PAPI pays for PrEP and related costs such as:

  • Office and medical copays.
  • Copays associated with required laboratory work.
  • Prescription copays that are not covered by a patient assistance program.
  • Medical services for people who are not eligible for insurance.

To qualify for PAPI services you must:

  • Have a negative HIV status.
  • Live in Ohio.
  • Make less than $75,060 annually.

You can go to to find the PrEP navigator in your area. 

Ready, Set, PrEP is a program that offers free PrEP to individuals that qualify. To qualify you must:

  • Not have health insurance coverage for prescription drugs.
  • Have taken an HIV test and received a negative result before starting the program.
  • Have a prescription for PrEP.
  • Live in the United States, including tribal lands and territories.

Ready, Set, PrEP does not offer free tests or prescriptions, only the drug once you have a prescription. To find a clinic to get a free or low-cost prescription, visit

PAPI is for all Ohioans.

Ready, Set, PrEP is for people across the United States.

This information will be added permanently to the Resource page on our web site.

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